1363. Does Genotypic Testing Improve Treatment Outcomes in Drug-Resistant Tuberculosis?

Drug-resistant tuberculosis in Israel: risk factors and treatment outcomes.

SETTING All culture-positive tuberculosis (TB) isolates in Israel. OBJECTIVES To outline the magnitude of drug-resistant TB in Israel, describe treatment outcomes and identify risk factors. DESIGN Retrospective study of laboratory data of all strains of adult TB patients tested for resistance to first- and second-line anti-tuberculosis drugs between 1999 and 2010. RESULTS Of 4652 reported...

Drug-resistant tuberculosis in Central Mozambique: the role of a rapid genotypic susceptibility testing

BACKGROUND Genotypic molecular testing may be very helpful for tuberculosis (TB) drug-resistance surveillance and for treatment guidance in low resource settings. METHODS Descriptive analysis of M. tuberculosis isolates from Beira Central Hospital, Mozambique, during 2014-2015. Genotype MTBDRplus and MTBDRsl were used and patient medical records reviewed. To explore genotypic susceptibility p...

outcomes in adolescents undergoing treatment for drug-resistant tuberculosis in cape town, south africa, 2008-2013

background there is limited data on outcomes of adolescents with drug-resistant tuberculosis (dr-tb). objectives to describe patient outcomes and factors associated with outcomes of adolescents diagnosed with dr-tb in khayelitsha, south africa. patients and methods a retrospective analysis of data for adolescents aged 10-19 years who were diagnosed with dr-tb between january 2008 and august 201...

Treatment of drug-resistant tuberculosis

CLINICAL QUESTION What is the best approach to the treatment of drug-resistant tuberculosis (TB)? RESULTS Evidence-based treatment of drug-susceptible TB is the best means of preventing the development of drug-resistant disease. Suspecting the possibility of drug-resistant TB, and prompt detection of all forms of drug-resistant TB, not only multidrug-resistant and extensively drug-resistant T...

outcomes in adolescents undergoing treatment for drug-resistant tuberculosis in mumbai